1. Knowledge of Nature and Knowledge of the Mind

But certain objections are repeatedly raised against this principle of small changes, and not by the least ingenious naturalists, in that it is emphasized that such changes are actually only pathological in nature due to the rigidity of a living being's organs. If, therefore, the deformation of the swim bladder is ever so slight, it is something pathological, it cannot prove expedient, it must be cast off again; and it is precisely because such slight deformations are to be understood as pathological that no transformations of animal or vegetable organisms can come about in this way.